NEET PG Medical – 2019 – Question – 66
Krabbe’s disease is
a) Deficiency of Beta- Galactosylcermidase
b) Deficiency of aryl Sulphatase
c) Alpha galactosidase
d) Acid lipase
Show Answer
Correct Answer – A
Answer- A (Deficiency of Beta- Galactosylcermidase)
Krabbe disease is caused by mutations in the GALC gene located on chromosome 14 (14q31),which is inherited in an autosomal recessive manner. Mutations in the GALC gene cause a deficiency of an enzyme called Galactosylceramidase.
