NEET PG Medical – 2018 – Question – 55
Drug of choice for resistant rheumatic chorea?
a) Valproate
b) Haloperidol
c) Diazepam
d) Probenecid
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Correct Answer – A
Answer: – A – Valproate
- Valproate, Sulpiride, & diazepam are used for symptomatic treatment.
Acute Rheumatic Fever: - Abnormal immune response to group A streptococcal infection
- Commonly affecting the joints, heart, brain, and skin.
- Symptoms: Arthritis, related to carditis & chorea.
- Sydenham’s chorea / Chorea minor
- Characterized by rapid, uncoordinated jerking movements primarily affecting the face, hands and feet.
- Signs & symptoms of chorea usually do not respond well to treatment with antirheumatic agents
- Symptomatic treatment include anticonvulsants (eg, valproate, carbamazepine) and neuroleptics (eg, pimozide, haloperidol, risperidone, olanzapine