Pharmacology – Set 1 – General
1. A substance having affinity but no intrinsic activity is
a) Agonist
b) Partial agonist
c) Antagonist
d) Physiological antagonist
2. A substance having affinity and intrinsic activity is
a) Agonists
b) Partial agonist
c) Antagonist
d) Physiological antagonist
3. Detoxification or protective synthesis occurs by –
a) Oxidation
b) Reduction
c) Conjugation
d) All of the above
4. Which of the following drugs are highly protein bound
a) Digitalis
b) Warfarin
c) Phenytoin
d)Rifampicin
e) None of the above
5. Estimation of serum levels is essential in treatment with
a) Impiramine
b) Chlorpromazine
c) Lithium
d) Haloperidol
6. Elimination after 4 half lives in first order Kinetics is
a) 84%
b) 93%
c) 80.5%
d) 4.75%
7. The following undergoes high first pass metabolism
a) Propranolol
b) Amitryptyline
c) Labetalol
d)Acebetalol
8. Which of the following drugs do not enhance the effect of anti coagulants
a) Quinine
b) Griseofulvin
c) Salicylate
d) Phenylbutazone
9. Drugs which increase the metabolism of warfarin is/areÂ
a) Rifampicin
b) Septran
c) Phenylbutazone
d) Phenobarbitone
10. The Alkaline drug (Amidopyrine) is absorbed from
a) Stomach
b) Proximal small intestine
c) Distal small intestine
d) Colon
