NEET PG Medical – 2020 – Question -56
DOC of prophylaxis for motion sickness?
a) Promethazine
b) Prochlorperazine
c) Metoclopramide
d) Itopride
Show Answer
Correct Answer – A
Ans: A. Promethazine
Motion sickness:
- Antiemetics with the anticholinergic-antihistamine property are the first choice drugs for motion sickness.
- Antidopaminergic and anti-HT 3 drugs are less effective.
- All anti-motion sickness drugs act better when taken ½–1 hour before commencing the journey.
- Once sickness has started, it is more difficult to control; higher doses/parenteral administration may be needed.
Drugs Included:
- Promethazine, diphenhydramine, dimenhydrinate:
- These drugs afford protection of motion sickness for 4–6 hours.
Promethazine Theoclate:
- This salt of promethazine has been specially promoted as an antiemetic, but the action does not appear to be significantly different from promethazine HCl.
