NEET PG Medical – 2019 – Question – 69
Mechanism of action of buspirone is?
a) 5 HT1A partial agonism.
b) 5 HT1B antagonism.
c) 5 HT1B partial agonism.
d) 5 HT2C antagonism.
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Correct Answer – A
Ans. A. HT1A partial agonism
5 HT1A:
* Presynaptic autoreceptor.
* Modulates serotonin release.
Partial 5 HT1A agonists:
* Buspirone, isapirone, gepirone.
* Useful as anti-anxiety drug.
