NEET PG Medical – 2019 – Question – 49
In Kreb’s cycle and Urea cycle the linking amino acid is
a) Fumarate
b) Alanine
c) Arginine
d) Aspartate
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Correct Answer – D
Answer: D. Aspartate
Aspartate helps in condensation with citrulline to form argino succinic acid.
Arginosuccinic acid undergoes a lytic reaction to form Arginine and fumarate.
oxaloacetate , the keto acid obtained from aspartate is intermediate of TCA cycle.
Hence aspartate is a common intermediate of TCA cycle through oxaloacetate and urea cycle (directly)
