NEET PG Medical – 2018 – Question – 18
Components responsible for counter current mechanism in kidney are all except:
a) Sodium outflow in thick ascending limb
b) Water outflow in thin descending limb
c) Sodium outflow in thin ascending limb
d) Flow of tubular fluid from PCT to DCT
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Correct Answer – C
Answer: C. Sodium outflow in thin ascending limb
Counter-current system occurs in kidney
A system in which inflow runs parallel to, counter to, and in close proximity to the outflow for some distance.
2 countercurrent mechanisms available:
- Countercurrent multiplier at Loop of Henle
- Generate high medullary osmotic gradient pressure
- Countercurrent exchanger at vasa recta of medullary capillaries
- Helps in maintain the medullary osmotic pressure gradient
Substances involved in countercurrent mechanism include: - Sodium actively absorbed with co-transport of potassium & chlorine in thick ascending limb of loop of Henle.
- Water reabsorbed in thin descending limb of loop of Henle.
- Urea diffuse out from the medullary collecting ducts into medullary interstitium.