Microbiology Question 5
All are true regarding superantigens except?
1. Are medium sized proteins
2. Cause release of cytokines
3. Bind outside the antibody binding groove
4. Activate very large numbers of B cells
Show Answer
Answer : 4 Activate very large numbers of B cells
- Superantigens activate very large number of T cells.
- They are medium sized proteins which bind outside the antibody binding groove.
- They have high resistance to proteases.
- They cause release of cytokines resulting in massive proliferation of T lymphocytes.
Ref: Ananthanarayan and Paniker’s Textbook of Microbiology, 9th edition, p90.
