NEET PG Medical – 2018 – Question – 65
Sacubitril is,
a) ACE inhibitor
b) Neutral endopeptidase inhibitor
c) Calcium channel inhibitor
d) Beta adrenergic blocker
Show Answer
Correct Answer – B
Answer: B – Neuro-endopeptidase inhibitor
Sacubitril, a prodrug inhibiting neuro-endopeptidase enzyme Activated to Sacubitril,
Inhibiting enzyme Neprilysin (Neutral endopeptidases)
Combination drug used in heart failure patients
Usually combined with ACE inhibitors like valsartan in ratio of 1:1
