NEET PG Medical – 2018 – Question – 52
Which chromosome is responsible for the production of MIF?
a) Chromosome 16
b) Chromosome 22
c) X Chromosome
d) Y chromosome
Correct Answer – D
Answer: D – Y Chromosome
Anti-Mullerian Hormone (AMH) / Mullerian Inhibiting Factor (MIF);
Mullerian-inhibiting Hormone (MIH) / Mullerian-inhibiting Substance (MIS).
AMH – Downstream genes regulated by SRY pathway
SRY – Gene in “Sex determining region” – short arm of Y
chromosome – Testis determining factor.
Secreted by Sertoli cells of the testes.
The production of AMH is controlled by two autosomal gene loci.
Hormone code
Receptor code.
Glycoprotein hormone
Related to inhibin & activin
Member of the transforming growth factor-β (TGF-β)
Key roles are in growth differentiation and folliculogenesis.
