NEET PG Medical – 2019 – Question – 94
Filgrastim is used in treatment of:
a) Anemia
b) Neutropenia
c) Malaria
d) Filarial
Show Answer
Correct Answer – B
Ans. is. B. Neutropenia
Filgrastim is a recombinant human granulocyte colony stimulating factor (G-CSF) which is a 175 – aminoacid glyco-protein.
It differs from the natural granulocyte stimulating factor due to its lack in glycosylation and the presence of an extra N-terminal methionine. It has proved to be effective in the treatment of severe neutropenia.
Ref: Goodman and Gilman’s The Pharmacological Basis of Therapeutics, 11th Edition, Pages 1429-32; Immunopharmacology
By Manzoor M. Khan, Pages 49-50
