NEET PG Medical – 2019 – Question – 80
Mechanism of action of Oseltamivir?
a) Protein synthesis inhibitor
b) Thymidylate synthetase inhibitor
c) Neuraminidase inhibitor
d) Pyrimidine analogs.
Show Answer
Correct Answer – C
Ans. C. Neuraminidase inhibitor
Neuraminidase inhibitors:
- Analogs of sialic acid.
- Interferes with release of progeny influenza A & B virus from infected host cells.
- Competitively & reversibly interact with active enzyme site –> resulting in clumping of newly released influenza virions to each other & to membrane of infected cell.
