NEET PG Medical – 2019 – Question – 79
A drug with high plasma binding protein property has which of the following properties?
a) Less GFR
b) Less drug interaction
c) Higher volume of distribution
d) Less tubular secretion
Show Answer
Correct Answer – A
Ans. A. Lesser GFR
Only free drugs can be filtered through glomerulus.
Hence, PPB decreases GFR.
Tubular secretion is an energy requiring carrier mediated active transport.
Hence , PPB do not interfere with tubular secretion.
