NEET PG Medical – 2019 – Question – 71
Which is the following is orally active direct Xa inhibitor?
a) Rivaroxaban
b) Agrataban
c) Dabigatran
d) Bilverudin
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Correct Answer – A
Ans. A. Synthesis of ergosterol
Inhibition of 14a-lanosterol demethylase, a key enzyme in ergosterol biosynthesis ? resulting in depletion of ergosterol & accumulation of toxic 14a-methylated sterols in membranes of susceptible yeast species ? Destruction of fungus.