NEET PG Medical – 2020 – Question – 90
Which interleukin responsible for producing IgE from B cells?
a) IL 1
b) IL 3
c) IL 4
d) Both B & C
Show Answer
Correct Answer – C
Answer- C, IL 4
IgE is produced by plasma cells located in lymph nodes draining the site of antigen entry or locally, at the sites of allergic reactions, by plasma cells derived from germinal centers developing within the inflamed tissue.
IgE antibody production requires TH2 cells that produce interleukin-4 (IL-4) and IL-13 and it can be inhibited by TH1 cells that produce interferon-γ (IFN-γ).
https://www.ncbi.nlm.nih.gov/books/NBK27117/
