NEET PG Medical – 2018 – Question – 40
TRALI occurs within how many hours of transfusion?
a) 48 Hrs
b) 72 Hrs
c) 6 Hrs
d) 12 Hrs
Show Answer
Correct Answer – C
Answer: C – 6 Hrs
Transfusion-Related Acute Lung Injury (TRALI) – Syndrome characterized by acute respiratory distress following transfusion.
Symptoms:
- Typically develop during, or within 6 hours of transfusion.
- Rapid onset of dyspnea & tachypnea.
- Associated fever, cyanosis, & hypotension.
Clinical examination: - Reveals respiratory distress.
- Pulmo nary crackles may be present with no signs of CHF or volume overload.
- CXR – Evidence of B/L pulmonary edema unrelated to CHF (noncardiogenic pulmonary edema),
- Bilat eral patchy infiltrates rapidly progressing to complete “white out” indistinguishable from Acute Respi ratory Distress Syndrome (ARDS).