NEET PG Medical – 2019 – Question – 45
Type of cholesterol present in gallstones?
a) Amorphous cholesterol monohydrate.
b) Amorphous cholesterol dihydrate.
c) Crystalline Cholesterol dihydrate.
d) Crystalline cholesterol monohydrate.
Correct Answer – D
Answer: D. Crystalline cholesterol monohydrate.
Gallstones are hardened deposits of digestive fluid that can form in your gallbladder.
The most common type of gallstone, called a cholesterol gallstone, often appears yellow in color. These gallstones are composed mainly of undissolved cholesterol.
Precipitation of solid cholesterol crystals from supersaturated bile has an essential role in cholesterol gallstone formation.
Gallstones are composed principally of cholesterol monohydrate crystals (cholesterol stones) or the acid salt of calcium bilirubinate (pigment stones).
When bile is concentrated in the gallbladder, it can become supersaturated with these substances, which then precipitate from the solution as microscopic crystals. The crystals are trapped in gallbladder mucus, producing gallbladder sludge.