NEET PG Medical – 2019 – Question – 41
A 25 year old alcoholic presented with edema, hypertension, ocular disturbance, and changes in mental state was observed, diagnosis of high output cardiac failure was made with Wet Beri Beri, this is due to deficiency of?
a) Vit B3
b) Vit B6
c) Vit B9
d) Vit B1
Correct Answer – D
Answer: D. Vit B1
Wet beriberi is the term used for thiamine deficiency with cardiovascular involvement.
In the first stage, peripheral vasodilation occurs, leading to a high cardiac output state. This leads to salt and water retention mediated through the renin-angiotensin-aldosterone system in the kidneys.
A more rapid form of wet beriberi is termed acute fulminant cardiovascular beriberi, or Shoshin beriberi.
The predominant injury is to the heart, and rapid deterioration follows the inability of the heart muscle to satisfy the body’s
demands because of its own injury.
In this case, edema may not be present. Instead, cyanosis of the hands and feet, tachycardia, distended neck veins, restlessness, and anxiety occur.
